Article
[Breast density and its association to polimorphism of the estrogen-receptor alpha gene Pvull and Xbal].
Ginecologia y obstetricia de Mexico - 1 May 2005
Murillo Ortiz Blanca, Pérez Luque Elva L, Malacara Juan Manuel
Abstract excerpt
OBJECTIVE: To study the influence of ER-alpha on mammographic density. MATERIAL AND METHODS: We selected 87 healthy women (age 49.8 +/- S.D. 6.12 years). We obtained the body mass index (BMI), and a fasting blood sample for hormone determinations and DNA extraction. ER-alpha genotyping was carried out by PCR and digestion with a Pvull and Xbal restriction endonucleases. Mammographic density was assigned by the...
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