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The Eukaryotic-Type Serine/Threonine Protein Kinase Stk Is Required for Biofilm Formation and Virulence in Staphylococcus epidermidis

23 Sept 2011

Abstract excerpt

BACKGROUND: Serine/threonine kinases are involved in gene regulation and signal transduction in prokaryotes and eukaryotes. Here, we investigated the role of the serine/threonine kinase Stk in the opportunistic pathogen Staphylococcus epidermidis. METHODOLOGY/PRINCIPAL FINDINGS: We constructed an isogenic stk mutant of a biofilm-forming clinical S. epidermidis isolate. Presence of stk was important for biofilm...

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Share to Antimicrobial Resistance in Staphylococcus
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PMID: 21966513
DOI: 10.1371/journal.pone.0025380

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