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MicroRNA 135 Regulates HOXA10 Expression in Endometriosis

28 Sept 2011

Abstract excerpt

CONTEXT: Homeo box A10 (HOXA10) regulates endometrial receptivity and its expression is decreased in women with endometriosis. Although sex steroids regulate HOXA10, these hormones are unaltered in endometriosis. We hypothesized a role for microRNA in the regulation of HOXA10. OBJECTIVE: MicroRNA 135a and -b are small noncoding RNA with predicted targets that include HOXA10. We evaluated miR135a/b expression and...

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PMID: 21956427
DOI: 10.1210/jc.2011-1231

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