Article
Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer.
Gynecologic oncology - 1 Dec 2011
Bondurant Amy E, Huang Zhiqing, Whitaker Regina S, Simel Lauren R, Berchuck Andrew, Murphy Susan K
Abstract excerpt
OBJECTIVE: Detection of cell free tumor-specific DNA methylation has been proposed as a potentially useful noninvasive mechanism to detect malignancies, including ovarian cancer, and to monitor response to treatment. However, there are few easily implemented quantitative approaches available for DNA methylation analysis. Our objectives were to develop an absolute quantitative method for detection of DNA...
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