Article
Monocytes can be induced to express lymphatic phenotypes.
Lymphology - 1 Jun 2011
Changming W, Xin L, Hua T, Shikun W, Qiong X, Zhigeng Z, Xueying W
Abstract excerpt
Although it has been recently shown that monocytes can transdifferentiate into blood vascular endothelial cells which are involved in angiogenesis, little attention has been paid to their potential to transdifferentiate into lymphatic endothelial cells. Therefore, we examined this question in our study. We first stimulated monocytes with either fibronectin (FN), VEGF-C, TNF-alpha, LPS, or IL-3 for 24h. Then we...
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