Article
Kinetic and sequence-structure-function analysis of known LinA variants with different hexachlorocyclohexane isomers.
PloS one - 1 Jan 2011
Sharma Pooja, Pandey Rinku, Kumari Kirti, Pandey Gunjan, Jackson Colin J, Russell Robyn J, Oakeshott John G, Lal Rup
Abstract excerpt
BACKGROUND: Here we report specific activities of all seven naturally occurring LinA variants towards three different isomers, α, γ and δ, of a priority persistent pollutant, hexachlorocyclohexane (HCH). Sequence-structure-function differences contributing to the differences in their stereospecificity for α-, γ-, and δ-HCH and enantiospecificity for (+)- and (-)-α -HCH are also discussed. METHODOLOGY/PRINCIPAL...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.