Article
Association between clonogenic cell growth and clinical risk group in B-cell chronic lymphocytic leukemia.
Blood - 1 Jul 1990
Dadmarz R, Rabinowe S N, Cannistra S A, Andersen J W, Freedman A S, Nadler L M
Abstract excerpt
Chronic lymphocytic leukemia of B-cell origin (B-CLL) is a disease with a variable clinical course, despite the fact that the neoplastic cells in this disorder are homogeneous with respect to morphology, immunophenotype, and cell cycle stage. To further investigate the heterogeneity observed in the clinical behavior of B-CLL, we determined the phenotype and growth requirements of clonogenic cells from 28 patients...
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