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Article

Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma

21 Sept 2011

Abstract excerpt

BACKGROUND: Downregulation of the putative tumor suppressor gene SLC22A18 has been reported in a number of human cancers. The aim of this study was to investigate the relationship between SLC22A18 downregulation, promoter methylation and the development and progression of human glioma. METHOD: SLC22A18 expression and promoter methylation was examined in human gliomas and the adjacent normal tissues. U251 glioma...

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PMID: 21936894
DOI: 10.1186/1479-5876-9-156

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