Article
The Val66Met polymorphism of the BDNF gene in anorexia nervosa: new data and a meta-analysis.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Aug 2013
Brandys Marek K, Kas Martien J H, van Elburg Annemarie A, Ophoff Roel, Slof-Op't Landt Margarita C T, Middeldorp Christel M, Boomsma Dorret I, van Furth Eric F, Slagboom P Eline, Adan Roger A H
Abstract excerpt
OBJECTIVES: The Val66Met polymorphism (rs6265) of the BDNF gene is a non-synonymous polymorphism, previously associated with anorexia nervosa (AN). METHODS: We genotyped rs6265 in 235 patients with AN and 643 controls. Furthermore, we performed a systematic review of all case-control and family-based studies testing this SNP in AN, and combined the results in a meta-analysis. RESULTS: The results of the...
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