Article
Modeled microgravity increases filamentation, biofilm formation, phenotypic switching, and antimicrobial resistance in Candida albicans.
Astrobiology - 1 Oct 2011
Searles Stephen C, Woolley Christine M, Petersen Rachel A, Hyman Linda E, Nielsen-Preiss Sheila M
Abstract excerpt
Candida albicans is an opportunistic fungal pathogen responsible for a variety of cutaneous and systemic human infections. Virulence of C. albicans increases upon exposure to some environmental stresses; therefore, we explored phenotypic responses of C. albicans following exposure to the environmental stress of low-shear modeled microgravity. Upon long-term (12-day) exposure to low-shear modeled microgravity, C....
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