Article
Genetic analysis of serum osteocalcin and bone mineral in multigenerational Afro-Caribbean families.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 May 2012
Kuipers A L, Gundberg C, Kammerer C M, Dressen A S, Nestlerode C S, Patrick A L, Wheeler V W, Bunker C H, Newman A B, Zmuda J M
Abstract excerpt
UNLABELLED: Osteocalcin is a major component of bone matrix. Concentrations of total, carboxylated, and uncarboxylated osteocalcin, are highly heritable and genetically correlated with bone mineral content (BMC) within African ancestry families. INTRODUCTION: Osteocalcin (OC) is a protein constituent of bone matrix and a marker of bone formation. We characterized the heritability of serum OC measures and...
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