Impact of TCF4 on the genetics of schizophrenia.

doi:10.1007/s00406-011-0256-9

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Article

Impact of TCF4 on the genetics of schizophrenia.

European archives of psychiatry and clinical neuroscience - 1 Nov 2011

Lennertz Leonhard, Quednow Boris B, Benninghoff Jens, Wagner Michael, Maier Wolfgang, Mössner Rainald

Abstract excerpt

Mutations of the transcription factor 4 (TCF4) gene cause mental retardation with or without associated facial dysmorphisms and intermittent hyperventilation. Subsequently, a polymorphism of TCF4 was shown in a genome-wide association study to slightly increase the risk of schizophrenia. We have further analysed the impact of this TCF4 variant rs9960767 on early information processing and cognitive functions in...

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PMID: 21932083
DOI: 10.1007/s00406-011-0256-9

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TCF4

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