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Article

Path to facilitate the prediction of functional amino acid substitutions in red blood cell disorders--a computational approach.

PloS one - 1 Jan 2011

B Rajith, C George Priya Doss

Abstract excerpt

BACKGROUND: A major area of effort in current genomics is to distinguish mutations that are functionally neutral from those that contribute to disease. Single Nucleotide Polymorphisms (SNPs) are amino acid substitutions that currently account for approximately half of the known gene lesions respo...

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Identifiers

PMID: 21931771
DOI: 10.1371/journal.pone.0024607
PMCID: PMC3172254

Genes

PKLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21931771-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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