Article
Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA.
Antimicrobial agents and chemotherapy - 1 Dec 2011
Escudero Jose Antonio, San Millan Alvaro, Gutierrez Belen, Hidalgo Laura, La Ragione Roberto M, AbuOun Manal, Galimand Marc, Ferrándiz María José, Domínguez Lucas, de la Campa Adela G, Gonzalez-Zorn Bruno
Abstract excerpt
Streptococcus suis is an emerging zoonotic pathogen. With the lack of an effective vaccine, antibiotics remain the main tool to fight infections caused by this pathogen. We have previously observed a reserpine-sensitive fluoroquinolone (FQ) efflux phenotype in this species. Here, SatAB and SmrA, two pumps belonging to the ATP binding cassette (ABC) and the major facilitator superfamily (MFS), respectively, have...
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