Article
Multicentric reticulohistiocytosis. Detailed immunophenotyping confirms macrophage origin.
The American journal of surgical pathology - 1 Jul 1990
Salisbury J R, Hall P A, Williams H C, Mangi M H, Mufti G J
Abstract excerpt
A case study of multicentric reticulohistiocytosis is presented with extensive immunohistochemical studies of the infiltrate in both paraffin and cryostat sections. These studies showed that the cells are of monocyte/macrophage origin. B- and T-cell gene rearrangement analysis of multicentric reticulohistiocytosis was also performed and showed a germline configuration.
Topics
- Cell Line
- Histiocytosis, Non-Langerhans-Cell
- Histocytochemistry
- Humans
- Immunohistochemistry
- Immunologic Techniques
- Macrophages
- Male
- Middle Aged
- Phenotype