The zon laboratory guide to positional cloning in zebrafish.

doi:10.1016/B978-0-12-374814-0.00016-1

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Article

The zon laboratory guide to positional cloning in zebrafish.

Methods in cell biology - 1 Jan 2011

Zhou Yi, Zon Leonard I

Abstract excerpt

Zebrafish genome sequencing project has improved efficiency of positional cloning in zebrafish and traditional chromosome walking by isolating large insert genomic libraries has become a past. However, the genetic principles underlying the positional cloning still form the foundation for current chromosome walking using the genome sequence assemblies and related genomic sequence and clone information. This guide...

Topics

Animal Husbandry
Animals
Chromosome Mapping
Cloning, Molecular
DNA
Female
Genetic Association Studies
Genetic Linkage
Genetic Markers
Humans
Larva
Male
Mutation
Phenotype
Polymorphism, Single Nucleotide
Real-Time Polymerase Chain Reaction
Sequence Analysis, DNA
Synteny

Source

Open in PubMed

Identifiers

PMID: 21924169
DOI: 10.1016/B978-0-12-374814-0.00016-1

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