Article
Systematic analysis of in vitro chemosensitivity and mib-1 expression in molecular breast cancer subtypes.
European journal of cancer (Oxford, England : 1990) - 1 Sept 2012
Liedtke Cornelia, Packeisen Jens, Hess Kenneth R, Vogt Ulf, Kiesel Ludwig, Kersting Christian, Korsching Eberhardt, Brandt Burkhard, Buerger Horst
Abstract excerpt
BACKGROUND: Molecular breast cancer subgroups show differences with regard to prognosis and response to chemotherapy. In vitro chemotherapy sensitivity and resistance assays (CSRAs) are a means to directly evaluate tumour cell response to a given drug. METHODS: Using tissue microarray (TMA) analysis, 550 invasive breast cancers were investigated for the expression of oestrogen receptor (ER), progesterone receptor...
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