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Article

cAMP During HIV Infection: Friend or Foe?

15 Sept 2011

Abstract excerpt

Intracellular levels of cyclic adenosine 3',5'-monophosphate (cAMP) are important regulators of immune cells, partially determining the balance between activation and suppression. In this review, we discuss the mechanisms by which HIV infection increases cAMP levels in T cells, as well as the effect of cAMP on HIV-specific responses and its effect on HIV replication and infection. Results suggest that increased...

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PMID: 21916808
DOI: 10.1089/aid.2011.0265

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