Article
The auto-regulation model: a unified concept of how HIV regulates its infectivity, pathogenesis and persistence.
International reviews of immunology - 1 Jan 1992
Layne S P, Dembo M
Abstract excerpt
The life cycle of HIV can be divided into two distinct stages: intracellular and extracellular. The prevailing view is that the intracellular stage provides the only locus for regulating the virus in response to physiologic stimuli. Such regulation is accomplished by modulating the rates of trans...
Topics
- CD4 Antigens
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV Infections
- HIV-1
- Homeostasis
- Humans
- Models, Biological
- Phenotype
- Viral Envelope Proteins