Article
A conserved lysine residue of plant Whirly proteins is necessary for higher order protein assembly and protection against DNA damage.
Nucleic acids research - 1 Jan 2012
Cappadocia Laurent, Parent Jean-Sébastien, Zampini Eric, Lepage Etienne, Sygusch Jurgen, Brisson Normand
Abstract excerpt
All organisms have evolved specialized DNA repair mechanisms in order to protect their genome against detrimental lesions such as DNA double-strand breaks. In plant organelles, these damages are repaired either through recombination or through a microhomology-mediated break-induced replication pathway. Whirly proteins are modulators of this second pathway in both chloroplasts and mitochondria. In this precise...
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