Article
A mutation leading to super-assembly of twin-arginine translocase (Tat) protein complexes.
Biochimica et biophysica acta - 1 Sept 2014
Patel Roshani, Vasilev Cvetelin, Beck Daniel, Monteferrante Carmine G, van Dijl Jan Maarten, Hunter C Neil, Smith Corinne, Robinson Colin
Abstract excerpt
The Tat system transports folded proteins across the bacterial plasma membrane. The mechanism is believed to involve coalescence of a TatC-containing unit with a separate TatA complex, but the full translocation complex has never been visualised and the assembly process is poorly defined. We report the analysis of the Bacillus subtilis TatAyCy system, which occurs as separate TatAyCy and TatAy complexes at steady...
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