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Article

Modeling the diagnostic criteria for alcohol dependence with genetic animal models.

Current topics in behavioral neurosciences - 1 Jan 2013

Crabbe John C, Kendler Kenneth S, Hitzemann Robert J

Abstract excerpt

A diagnosis of alcohol dependence (AD) using the DSM-IV-R is categorical, based on an individual's manifestation of three or more symptoms from a list of seven. AD risk can be traced to both genetic and environmental sources. Most genetic studies of AD risk implicitly assume that an AD diagnosis represents a single underlying genetic factor. We recently found that the criteria for an AD diagnosis represent three...

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PMID: 21910077
DOI: 10.1007/7854_2011_162
PMCID: PMC3371181

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Source receipt: pubmed, retrieved 7 Sept 2026.

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