Article
Determination of the source of androgen excess in functionally atypical polycystic ovary syndrome by a short dexamethasone androgen-suppression test and a low-dose ACTH test.
Human reproduction (Oxford, England) - 1 Nov 2011
Rosenfield Robert L, Mortensen Monica, Wroblewski Kristen, Littlejohn Elizabeth, Ehrmann David A
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) patients typically have 17-hydroxyprogesterone (17OHP) hyperresponsiveness to GnRH agonist (GnRHa) (PCOS-T). The objective of this study was to determine the source of androgen excess in the one-third of PCOS patients who atypically lack this type of ovarian dysfunction (PCOS-A). METHODS: Aged-matched PCOS-T (n= 40), PCOS-A (n= 20) and controls (n= 39) were studied...
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