Article
Mechanisms involved in the development of chronic hepatitis C as potential targets of antiviral therapy.
Current pharmaceutical biotechnology - 1 Nov 2011
Jackowiak Paulina, Figlerowicz Magdalena, Kurzyńska-Kokorniak Anna, Figlerowicz Marek
Abstract excerpt
At present, about 3% of the human population are infected with hepatitis C virus (HCV). The first, acute stage of the disease is usually asymptomatic. However, only 15-25% of the infected eliminate the virus, while the remaining patients develop chronic hepatitis C (CHC). After 10-30 years of CHC, cirrhosis occurs in 20-30% of patients; 5-10% of this group eventually suffer from hepatocellular carcinoma....
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