Article
Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
Obesity (Silver Spring, Md.) - 1 Nov 2011
McGuire Timothy R, Brusnahan Susan K, Bilek Laura D, Jackson John D, Kessinger M Anne, Berger Anne M, Garvin Kevin L, O'Kane Barbara J, Tuljapurkar Sonal R, Sharp John G
Abstract excerpt
The purpose of this study was to assess the inflammatory nature of obesity and its effect on blood and bone marrow endothelial cell populations. Obese patients (BMI ≥30) had significantly higher concentrations of the inflammatory marker C-reactive protein (CRP) (P = 0.03) and lower concentrations of the anti-inflammatory cytokine interleukin-10 (IL-10) (P = 0.05). This cytokine profile is consistent with obesity...
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