Article
Circulating activated endothelial cells in pediatric obesity.
The Journal of pediatrics - 1 Oct 2010
Kelly Aaron S, Hebbel Robert P, Solovey Anna N, Schwarzenberg Sarah Jane, Metzig Andrea M, Moran Antoinette, Sinaiko Alan R, Jacobs David R, Steinberger Julia
Abstract excerpt
OBJECTIVE: We characterized the state of the vascular endothelium in pediatric obesity by comparing circulating endothelial cell (CEC) number and activation phenotype in severely obese children to that of normal weight, overweight, and obese children. STUDY DESIGN: We used immunohistochemical examination of buffy-coat smears to enumerate CEC and immunofluorescence microscopy to quantify activated CEC in 107...
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