Article
Genome-wide association study of HPV seropositivity.
Human molecular genetics - 1 Dec 2011
Chen Dan, McKay James D, Clifford Gary, Gaborieau Valérie, Chabrier Amélie, Waterboer Tim, Zaridze David, Lissowska Jolanta, Rudnai Peter, Fabianova Eleonora, Bencko Vladimir, Janout Vladimir, Foretova Lenka, Mates Ioan Nicolae, Szeszenia-Dabrowska Neonila, Curado Maria Paula, Koifman Sergio, Menezes Ana, Wünsch-Filho Victor, Eluf-Neto José, Fernández Garrote Leticia, Matos Elena, Zelenika Diana, Boland Anne, Boffetta Paolo, Pawlita Michael, Lathrop Mark, Brennan Paul
Abstract excerpt
High-risk α mucosal types of human papillomavirus (HPV) cause anogenital and oropharyngeal cancers, whereas β cutaneous HPV types (e.g. HPV8) have been implicated in non-melanoma skin cancer. Although antibodies against the capsid protein L1 of HPV are considered as markers of cumulative exposure, not all infected persons seroconvert. To identify common genetic variants that influence HPV seroconversion, we...
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