Article
Genetic modifiers of non-alcoholic fatty liver disease progression.
Biochimica et biophysica acta - 1 Nov 2011
Anstee Quentin M, Daly Ann K, Day Christopher P
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is now recognised as the most common cause of liver dysfunction worldwide. However, whilst the majority of individuals who exhibit features of the metabolic syndrome including obesity and insulin resistance will develop steatosis, only a minority progress to steatohepatitis, fibrosis and cirrhosis. Subtle inter-patient genetic variations and environment interact to...
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