Article
[Influence of genetic mutations on clinical presentation of subretinal neovascularization. Report 1: The impact of CFH and IL-8 genes polymorphism].
Vestnik oftalmologii - 1 Jan 2000
Budzinskaia M V, Pogoda T V, Generozov É V, Chikun E A, Shchegoleva I V, Kazarian É É, Galoian N S
Abstract excerpt
Genetic analysis was performed in patients with subretinal neovascularization (CNV). The results showed significant association of CFH (compliment factor H) gene polymorphism with increase (rs1061170, rs514943 and rs380390) or decrease (rs529825, rs7524776, rs1831281, , , , ) of CNV development risk. The incidence of IL-8 gene mutation was significantly (p = 0.008) higher in...