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Article

ApoE is required for maintenance of the dentate gyrus neural progenitor pool.

Development (Cambridge, England) - 1 Oct 2011

Yang Cui-Ping, Gilley Jennifer A, Zhang Gui, Kernie Steven G

Abstract excerpt

Many genes regulating adult neurogenesis have been identified and are known to play similar roles during early neuronal development. We recently identified apolipoprotein E (ApoE) as a gene the expression of which is essentially absent in early brain progenitors but becomes markedly upregulated in adult dentate gyrus stem/progenitor cells. Here, we demonstrate that ApoE deficiency impairs adult dentate gyrus...

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Identifiers

PMID: 21880781
DOI: 10.1242/dev.065540
PMCID: PMC3177307

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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