Article
The isolation of osmotic-remedial conditional lethal mutants of Candida albicans.
Current genetics - 1 Apr 1990
Payton M A, de Tiani M
Abstract excerpt
We have developed a method for the isolation of a broad range of conditional lethal mutants of the pathogenic fungus Candida albicans. The method substantially alleviates the problems posed by the diploid nature, and the biased mutant spectrum, exhibited by most strains of this organism. We have...
Topics
- Candida albicans
- Cell Wall
- Culture Media
- Genes, Fungal
- Genes, Lethal
- Mutation
- Osmotic Fragility
- Phenotype
- Temperature
