Article
Comparative analysis of EspF variants in inhibition of Escherichia coli phagocytosis by macrophages and inhibition of E. coli translocation through human- and bovine-derived M cells.
Infection and immunity - 1 Nov 2011
Tahoun Amin, Siszler Gabriella, Spears Kevin, McAteer Sean, Tree Jai, Paxton Edith, Gillespie Trudi L, Martinez-Argudo Isabel, Jepson Mark A, Shaw Darren J, Koegl Manfred, Haas Juergen, Gally David L, Mahajan Arvind
Abstract excerpt
The EspF protein is secreted by the type III secretion system of enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC, respectively). EspF sequences differ between EHEC O157:H7, EHEC O26:H11, and EPEC O127:H6 in terms of the number of SH3-binding polyproline-rich repeats and specific residues in these regions, as well as residues in the amino domain involved in cellular localization. EspF(O127)...
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