Article
Local injections of adipose-derived mesenchymal stem cells modulate inflammation and increase angiogenesis ameliorating the dystrophic phenotype in dystrophin-deficient skeletal muscle.
Stem cell reviews and reports - 1 Jun 2012
Pinheiro Carlos Hermano da Justa, de Queiroz Jean César Farias, Guimarães-Ferreira Lucas, Vitzel Kaio Fernando, Nachbar Renato Tadeu, de Sousa Luís Gustavo Oliveira, de Souza Alcione Lescano, Nunes Maria Tereza, Curi Rui
Abstract excerpt
The effects of adipose-derived mesenchymal stem cells (ADMSC) transplantation on degeneration, regeneration and skeletal muscle function were investigated in dystrophin-deficient mice (24-week-old). ADMSC transplantation improved muscle strength and, resistance to fatigue. An increase in fiber cr...
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