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Article

Regenerative potential of TGFβ3 + Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Mar 2012

Abbott Rosalyn Delia, Purmessur Devina, Monsey Robert Daniel, Iatridis James Christopher

Abstract excerpt

Injection of soluble cell signaling factors into degenerated intervertebral discs (IVDs) offers a minimally invasive treatment that could limit the processes of degeneration by stimulating native matrix repair. This study evaluated the regenerative capacity of degenerated nucleus pulposus (NP) cells obtained from patients undergoing anterior interbody fusions by measuring metabolic activity, DNA content,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21866573
DOI: 10.1002/jor.21534
PMCID: PMC3264846

Genes

ADAMTS5
MMP1
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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