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Article

Host Regulatory Network Response to Infection with Highly Pathogenic H5N1 Avian Influenza Virus

25 Aug 2011

Abstract excerpt

During the last decade, more than half of humans infected with highly pathogenic avian influenza (HPAI) H5N1 viruses have died, yet virus-induced host signaling has yet to be clearly elucidated. Airway epithelia are known to produce inflammatory mediators that contribute to HPAI H5N1-mediated pathogenicity, but a comprehensive analysis of the host response in this cell type is lacking. Here, we leveraged a system...

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PMID: 21865398
DOI: 10.1128/jvi.05792-11

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