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Article

Essential Impact of NF-κB Signaling on the H5N1 Influenza A Virus-Induced Transcriptome

28 Sept 2009

Abstract excerpt

Systemic infections of humans and birds with highly pathogenic avian influenza A viruses of the H5N1 subtype are characterized by inner bleedings and a massive overproduction of cytokines known as cytokine storm. Growing evidence supports the role of endothelial cells in these processes. The aim of this study was to elucidate determinants of this strong response in endothelial cells with a focus on the...

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PMID: 19786538
DOI: 10.4049/jimmunol.0804198

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