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Article

5' End-independent RNase J1 endonuclease cleavage of Bacillus subtilis model RNA.

The Journal of biological chemistry - 7 Oct 2011

Deikus Gintaras, Bechhofer David H

Abstract excerpt

Bacillus subtilis trp leader RNA is a small (140-nucleotide) RNA that results from attenuation of trp operon transcription upon binding of the regulatory TRAP complex. Previously, endonucleolytic cleavage by ribonuclease RNase J1 in a 3'-proximal, single-stranded region was shown to be critical for initiation of trp leader RNA decay. RNase J1 is a dual-specificity enzyme, with both 5' exonucleolytic and...

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Identifiers

PMID: 21862575
DOI: 10.1074/jbc.M111.287409
PMCID: PMC3186403

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