Multiple roles of RNase Y in Streptococcus pyogenes mRNA processing and degradation.

Abstract excerpt

Control over mRNA stability is an essential part of gene regulation that involves both endo- and exoribonucleases. RNase Y is a recently identified endoribonuclease in Gram-positive bacteria, and an RNase Y ortholog has been identified in Streptococcus pyogenes (group A streptococcus [GAS]). In this study, we used microarray and Northern blot analyses to determine the S. pyogenes mRNA half-life of the...

Topics

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• Blotting, Northern
• DNA, Complementary
• Endoribonucleases
• Half-Life
• RNA, Bacterial