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Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns.

PloS one - 1 Jan 2011

Malik Assaf, Korol Abraham, Hübner Sariel, Hernandez Alvaro G, Thimmapuram Jyothi, Ali Shahjahan, Glaser Fabian, Paz Arnon, Avivi Aaron, Band Mark

Abstract excerpt

The blind subterranean mole rat (Spalax ehrenbergi superspecies) is a model animal for survival under extreme environments due to its ability to live in underground habitats under severe hypoxic stress and darkness. Here we report the transcriptome sequencing of Spalax galili, a chromosomal type of S. ehrenbergi. cDNA pools from muscle and brain tissues isolated from animals exposed to hypoxic and normoxic...

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Brain
DNA, Complementary
Gene Expression Profiling
Gene Library
Hypoxia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21857902
DOI: 10.1371/journal.pone.0021227
PMCID: PMC3155515

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