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Article

The Commensal Microbiota Drives Immune Homeostasis

1 Jan 2012

Abstract excerpt

For millions of years, microbes have coexisted with eukaryotic cells at the mucosal surfaces of vertebrates in a complex, yet usually harmonious symbiosis. An ever-expanding number of reports describe how eliminating or shifting the intestinal microbiota has profound effects on the development and functionality of the mucosal and systemic immune systems. Here, we examine some of the mechanisms by which bacterial...

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PMID: 22566917
DOI: 10.3389/fimmu.2012.00033

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