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Article

Suboptimal in vitro culture conditions: an epigenetic origin of long‐term health effects

1 May 2007

Abstract excerpt

The foetal origins of adult diseases or Barker hypothesis suggests that there can be adverse in uterus effects on the foetus that can lead to certain diseases in adults. Extending this hypothesis to the early stages of embryo development, in particular, to preimplantation stages, it was recently demonstrated that, long-term programming of postnatal development, growth and physiology can be irreversibly affected...

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Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

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PMID: 17474101
DOI: 10.1002/mrd.20746

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