Article
Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Mar 2012
Windemuth Andreas, de Leon Jose, Goethe John W, Schwartz Harold I, Woolley Stephen, Susce Margaret, Kocherla Mohan, Bogaard Kali, Holford Theodore R, Seip Richard L, Ruaño Gualberto
Abstract excerpt
The purpose of this study was to identify genetic variants predictive of cardiovascular risk factors in a psychiatric population treated with second generation antipsychotics (SGA). 924 patients undergoing treatment for severe mental illness at four US hospitals were genotyped at 1.2 million single nucleotide polymorphisms. Patients were assessed for fasting serum lipid (low density lipoprotein cholesterol...
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