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Article

Non-muscle myosin IIA is required for the development of the zebrafish glomerulus.

Kidney international - 1 Nov 2011

Müller Tobias, Rumpel Elisabeth, Hradetzky Susanne, Bollig Frank, Wegner Henny, Blumenthal Antje, Greinacher Andreas, Endlich Karlhans, Endlich Nicole

Abstract excerpt

Mutations in the MYH9 gene, coding for the non-muscle myosin heavy chain IIA (NMHC-IIA), are responsible for syndromes characterized by macrothrombocytopenia associated with deafness, cataracts, and severe glomerular disease. Electron microscopy of renal biopsies from these patients found glomerular abnormalities characterized by alterations in mesangial cells, podocytes, and thickening of the glomerular basement...

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Identifiers

PMID: 21849970
DOI: 10.1038/ki.2011.256

Genes

MYH9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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