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Article

Do serum angiopoietin-1, angiopoietin-2, and their receptor Tie-2 and 4G/5G variant of PAI-1 gene have a role in the pathogenesis of preeclampsia?

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Oct 2011

Kamal Manal, El-Khayat Waleed

Abstract excerpt

OBJECTIVE: To evaluate whether serum angiogenesis markers such as angiopoietins (Ang-1, Ang-2) and their receptor (Tie-2) are altered in women with preeclampsia. We also performed genotyping to determine if the 4G/5G genotypes of -675 PAI-1 gene may play a role in the pathogenesis of preeclampsia. MATERIALS AND METHODS: Sixty-eight pregnant women with preeclampsia were compared to 35 normotensive pregnant women...

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Source

Identifiers

PMID: 21849906
DOI: 10.2310/JIM.0b013e31822c5bdf

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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