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Article

HIF-1α effects on angiogenic potential in human small cell lung carcinoma

15 Aug 2011

Abstract excerpt

BACKGROUND: Hypoxia-inducible factor-1 alpha (HIF-1α) maybe an important regulatory factor for angiogenesis of small cell lung cancer (SCLC). Our study aimed to investigate the effect of HIF-1α on angiogenic potential of SCLC including two points: One is the effect of HIF-1α on the angiogenesis of SCLC in vivo. The other is the regulation of angiogenic genes by HIF-1α in vitro and in vivo. METHODS: In vivo we...

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PMID: 21843314
DOI: 10.1186/1756-9966-30-77

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