Article
Indirect repression by Bacillus subtilis CodY via displacement of the activator of the proline utilization operon.
Journal of molecular biology - 21 Oct 2011
Belitsky Boris R
Abstract excerpt
Proline is an efficient source of both carbon and nitrogen for many bacterial species. In Bacillus subtilis, the proline utilization pathway, encoded by the putBCP operon, is inducible by proline. Here, we show that this induction is mediated by PutR, a proline-responsive transcriptional activator of the PucR family. When other amino acids are present in the medium, proline utilization is prioritized through...
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