Article
Gene expression profiling in the lungs of patients with pulmonary hypertension associated with pulmonary fibrosis.
Chest - 1 Mar 2012
Mura Marco, Anraku Masaki, Yun Zhihong, McRae Karen, Liu Mingyao, Waddell Thomas K, Singer Lianne G, Granton John T, Keshavjee Shaf, de Perrot Marc
Abstract excerpt
BACKGROUND: Pulmonary hypertension (PH) associated with pulmonary fibrosis (PF) is a severe condition with poor outcome. It is unknown whether patients with PF with associated PH (APH) represent a distinct phenotype of the disease. We hypothesized that the lung tissue gene expression pattern of patients with APH has a characteristic profile when compared with patients with PF without APH. We sought to determine...
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