Article
Phenotype of resting and activated monocyte-derived dendritic cells grown from peripheral blood of patients with ankylosing spondylitis.
Inflammation - 1 Apr 2012
Slobodin Gleb, Kessel Aharon, Kofman Natalie, Toubi Elias, Rosner Itzhak, Odeh Majed
Abstract excerpt
Decreased levels of class II major histocompatibility complex (MHC) expression and impaired formation of immunological synapse by dendritic cells (DCs) of HLA-B27 transgenic rats have been recently demonstrated. The resulting dysfunction of DCs may be implicated in the pathogenesis of the HLA-B27-related disease in transgenic animals. The phenotype of DCs in patients with ankylosing spondylitis (AS) has not been...
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