Article
Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.
Cancer science - 1 Apr 2018
Fukai Emi, Sato Haruna, Watanabe Masatoshi, Nakae Dai, Totsuka Yukari
Abstract excerpt
Engineered nanomaterials (ENM) are now used in a wide variety of fields, and, thus, their safety should urgently be assessed and secured. It has been suggested that inflammatory responses via the phagocytosis of ENM by macrophages is a key mechanism for their genotoxicity. The present study was conducted to establish a mechanism-based assay to evaluate the genotoxicity of ENM under conditions simulating an in...
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