Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Removal of potentially confounding phenotypes from a Siamese-derived feline glaucoma breeding colony.

Comparative medicine - 1 Jun 2011

Rutz-Mendicino Michelle M, Snella Elizabeth M, Jens Jackie K, Gandolfi Barbara, Carlson Steven A, Kuehn Markus H, McLellan Gillian J, Ellinwood N Matthew

Abstract excerpt

Feline breeding colonies face genetic constraints involving founder effects. A Siamese-founded colony used to study primary congenital glaucoma displayed coat colors additional to the Siamese coat. Genes affecting pigment can exhibit pleiotropy on ocular development and function. To remove potentially confounding phenotypes from our colony, we documented the source and frequency of the Siamese allele at the gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Breeding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Founder Effect

Share to Glaucoma

Share to Membrane Glycoproteins

Share to Monophenol Monooxygenase

Source

Open in PubMed Open full text

Identifiers

PMID: 21819695
PMCID: PMC3123758

Genes

GLB1
MLPH
TYR
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Removal of potentially confounding phenotypes from a Siamese-derived feline glaucoma breeding colony.PMID 21819695Read ↗

Tyrosinase mutations associated with Siamese and Burmese patterns in the domestic cat (Felis catus).Semantic proximity Read ↗

Colour Variants in Siberian Cats: A Comprehensive Review of Phenotype, Genetics, and Breed Registry Standards.Semantic proximity Read ↗

Breed Distribution and Allele Frequencies of Base Coat Color, Dilution, and White Patterning Variants across 28 Horse Breeds.Semantic proximity Read ↗

Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed.Semantic proximity Read ↗

A frameshift mutation in the melanophilin gene causes the dilute coat colour in rabbit (Oryctolagus cuniculus) breeds.Semantic proximity Read ↗

Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation.Semantic proximity Read ↗

Molecular genetics of coat colour variations in White Galloway and White Park cattle.Semantic proximity Read ↗

Recurrent evolution of melanism in South American felids.Semantic proximity Read ↗

Golden cats: A never-ending story!Semantic proximity Read ↗

Siamese cat tyrosinase has enhanced proteasome degradation and increased cellular aggregationSemantic proximity Read ↗

Impact of white-spotting alleles, including W20, on phenotype in the American Paint Horse.Semantic proximity Read ↗

Mutation responsible for congenital photosensitivity and hyperbilirubinemia in Southdown sheep.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.